AlAr3(THF): highly efficient reagents for cross-couplings with aryl bromides and chlorides catalyzed by the economic palladium complex of PCy3.

Palladium-Catalyzed Amination of Aryl Chlorides and Bromides with Ammonium Salts

We report the palladium-catalyzed coupling of aryl halides with ammonia and gaseous amines as their ammonium salts. The coupling of aryl chlorides and ortho-substituted aryl bromides with ammonium sulfate forms anilines with higher selectivity for the primary arylamine over the diarylamine than couplings with ammonia in dioxane. The resting state for the reactions of aryl chlorides is different...

The First Method for Achieving Palladium-Catalyzed Cross- Couplings of Simple Alkyl Chlorides: Suzuki Reactions Catalyzed by Pd2(dba)3/PCy3

NiXantphos: A Deprotonatable Ligand for Room-Temperature Palladium-Catalyzed Cross-Couplings of Aryl Chlorides

Although the past 15 years have witnessed the development of sterically bulky and electron-rich alkylphosphine ligands for palladium-catalyzed cross-couplings with aryl chlorides, examples of palladium catalysts based on either triarylphosphine or bidentate phosphine ligands for efficient room temperature cross-coupling reactions with unactivated aryl chlorides are rare. Herein we report a pall...

Palladium-Catalyzed α-Arylation of Aryl Acetic Acid Derivatives via Dienolate Intermediates with Aryl Chlorides and Bromides

To date, examples of α-arylation of carboxylic acids remain scarce. Using a deprotonative cross-coupling process (DCCP), a method for palladium-catalyzed γ-arylation of aryl acetic acids with aryl halides has been developed. This protocol is applicable to a wide range of aryl bromides and chlorides. A procedure for the palladium-catalyzed α-arylation of styryl acetic acids is also described.

Monodisperse palladium nanoparticles supported on chemically derived graphene: highly active and reusable nanocatalysts for Suzuki–Miyaura cross-coupling reactions

Addressed herein is the catalysis of monodisperse palladium nanoparticles (NPs) supported on chemically derived graphene (CDG) for the Suzuki–Miyaura cross-coupling of phenylboronic acid and various aryl halides. Monodisperse Pd NPs were synthesized by the solution phase reduction of palladium(II) acetylacetonate with morpholine borane complex in oleylamine and deposited on CDG via the liquid p...